essential thrombocythemia การใช้

• Mutations to this gene are also associated with myelofibrosis and essential thrombocythemia.
• In essential thrombocythemia, mutations occur at position 505 or 515.
• A classic symptom of polycythemia vera ( and the related myeloproliferative disease essential thrombocythemia ) is erythromelalgia.
• There have also been cases reported in which hemopericardium was noted as an initial manifestation of essential thrombocythemia.
• Mutations in CALR have been found in the majority of " JAK2 " and MPL-negative essential thrombocythemia and myelofibrosis.
• Geron licensee essential thrombocythemia, a disorder in which the body overproduces blood platelets, increasing the risk of blood clots.
• JAK2V617F is a mutant of tyrosine kinase JAK2, is found in most patients with polycythemia vera ( PV ) and a substantial proportion of patients with idiopathic myelofibrosis or essential thrombocythemia.
• Agrylin is the first drug approved for treatment of essential thrombocythemia, a life-threatening blood disorder of unknown cause that results in an abnormally high level of platelets-- the tiny cells needed for clotting.
• In 2016, Firefighter Mike Wilson was introduced to a recipient from Erie, Pennsylvania, who received his lifesaving bone marrow to treat her acute myeloid leukemia ( AML ), while Firefighter Frank Perdue met a recipient diagnosed with essential thrombocythemia, a rare chronic blood disorder.